Leucocyte labelling with 99mTc-exametazime and polycythemia vera: a casual finding

Authors

  • Mónica Romero Otero Unidad de Radiofarmacia. Hospital Clínico Universitario de Valencia
  • Mar Soria-Merino Unidad de Radiofarmacia. Hospital Clínico Universitario de Valencia
  • Roberto Maestre-Cutillas Unidad de Radiofarmacia. Hospital Clínico Universitario de Valencia
  • Rafael Díaz-Expósito Servicio de Medicina Nuclear. Instituto Valenciano de Oncología, Valencia
  • Héctor Rodríguez-Parra Sección de Medicina Nuclear. Hospital Clínico Universitario de Valencia
  • Adela Cánoves-Llombart Sección de Medicina Nuclear. Hospital Clínico Universitario de Valencia
  • Jorge Sabater-Sancho Sección de Medicina Nuclear. Hospital Clínico Universitario de Valencia
  • Viviana Carrero-Vásquez Sección de Medicina Nuclear. Hospital Clínico Universitario de Valencia

DOI:

https://doi.org/10.30827/ars.v60i4.9410

Keywords:

polycythemia vera, labelled leukocytes, erythrocyte sedimentation rate

Abstract

The official World Health Organization classification of hematopoietic and lymphoid tissue tumors introduces in 2016 the concept of masked polycythemia vera (PV) and reveals that this entity has been underdiagnosed in the past. We present the case of a 49-year-old man, smoker, operated on for ankle fracture more than 15 years ago, referred to evaluate a possible associated infectious process. As there was no previous separation of the red blood cells by sedimentation during the leukocyte labelling procedure with 99mTc-exametazima, the causes of decreased erythrocyte sedimentation rate were reviewed. These include polyglobulia and smoking, both present in the patient. A haematological study was advised, which concluded with the diagnosis of PV. The indications of the specialist in Radiopharmacy allowed diagnosing a case not identified until then, although the patient had had symptoms for years.

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References

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Published

2019-06-20

How to Cite

1.
Romero Otero M, Soria-Merino M, Maestre-Cutillas R, Díaz-Expósito R, Rodríguez-Parra H, Cánoves-Llombart A, Sabater-Sancho J, Carrero-Vásquez V. Leucocyte labelling with 99mTc-exametazime and polycythemia vera: a casual finding. Ars Pharm [Internet]. 2019 Jun. 20 [cited 2024 Jul. 22];60(4):227-30. Available from: https://revistaseug.ugr.es/index.php/ars/article/view/9410

Issue

Section

Clinical Notes