Use of heat-denatured 99mTc-labeled red blood cells in the scintigraphic diagnosis of an infrequent case of intrathoracic splenosis

Authors

  • Mónica Romero Otero Unidad de Radiofarmacia. Hospital Clínico Universitario de Valencia
  • Roberto Cutillas Roberto Unidad de Radiofarmacia. Hospital Clínico Universitario de Valencia
  • Mar Soria-Merino Unidad de Radiofarmacia. Hospital Clínico Universitario de Valencia
  • Adela Cánoves Llombart Sección de Medicina Nuclear. Hospital Clínico Universitario de Valencia
  • Rafael Díaz Expósito Sección de Medicina Nuclear. Hospital Clínico Universitario de Valencia
  • Héctor Rodríguez Parra Sección de Medicina Nuclear. Hospital Clínico Universitario de Valencia
  • Jorge Sabater Sancho Sección de Medicina Nuclear. Hospital Clínico Universitario de Valencia

DOI:

https://doi.org/10.30827/ars.v59i4.8110

Keywords:

Intrathoracic splenosis, Scintigraphy, Radionuclide imaging

Abstract

Intrathoracic splenosis is extremely rare and is associated with previous history of rupture of the spleen and diaphragm caused by trauma. It is usually asymptomatic, presenting as an accidental finding in the X-ray images or computed tomography.

The definitive diagnosis can be made by scintigraphic studies associated with functional studies of particle or cell uptake. Due to its sensitivity and specificity, gammagraphy with heat-denatured 99mTc-labeled red blood cells is the reference technique for confirming the diagnosis of splenosis and differentiating it from other processes that require surgical resection.

We describe the case of a 52-year-old man treated for pleuritic pain in the left hemithorax. The images showed left pleural effusion and pulmonary infarction without signs of thromboembolism. There were multiple foci suggestive of splenosis, which was confirmed by splenic scintigraphy with heat-denatured 99mTc-labeled red blood cells.

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References

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Published

2018-12-20

How to Cite

1.
Romero Otero M, Cutillas Roberto R, Soria-Merino M, Cánoves Llombart A, Díaz Expósito R, Rodríguez Parra H, Sabater Sancho J. Use of heat-denatured 99mTc-labeled red blood cells in the scintigraphic diagnosis of an infrequent case of intrathoracic splenosis. Ars Pharm [Internet]. 2018 Dec. 20 [cited 2024 Jul. 22];59(4):259-62. Available from: https://revistaseug.ugr.es/index.php/ars/article/view/8110

Issue

Section

Clinical Notes