Immunomodulatory activity of methanol extract of flower-heads of Sphaeranthus indicus Linn

Authors

  • AR BAFNA Pharmacy Department, Faculty of Technology and Engineering, The M.S.University of Baroda,Vadodara-390002,Gujarat, India
  • SH MISHRA Pharmacy Department, Faculty of Technology and Engineering, The M.S.University of Baroda,Vadodara-390002,Gujarat, India

Keywords:

Sphaeranthus indicus, Immunomodulatory activity, Haemagglutination, Myelosuppression

Abstract

Methanol extract, its petroleum ether, chloroform and remaining methanol fractions, of flower heads of Sphaeranthusindicus Linn. were found effective in increasing phagocytic activity, haemagglutination antibody titer and delayed typehypersensitivity, whereas only remaining methanol fraction was found active in normalizing total WBC levels in caseof cyclophosphamide induced myelosuppression in mice. Present study, therefore, reveals that the drug holds promiseas immunomodulatory agent, which acts by stimulating both humoral as well as cellular immunity and phagocyticfunction

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References

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Published

2004-06-16

How to Cite

1.
BAFNA A, MISHRA S. Immunomodulatory activity of methanol extract of flower-heads of Sphaeranthus indicus Linn. Ars Pharm [Internet]. 2004 Jun. 16 [cited 2024 Jul. 22];45(3):281-9. Available from: https://revistaseug.ugr.es/index.php/ars/article/view/5115

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Original Articles