Immunomodulatory activity of methanol extract of flower-heads of Sphaeranthus indicus Linn
Keywords:
Sphaeranthus indicus, Immunomodulatory activity, Haemagglutination, MyelosuppressionAbstract
Methanol extract, its petroleum ether, chloroform and remaining methanol fractions, of flower heads of Sphaeranthusindicus Linn. were found effective in increasing phagocytic activity, haemagglutination antibody titer and delayed typehypersensitivity, whereas only remaining methanol fraction was found active in normalizing total WBC levels in caseof cyclophosphamide induced myelosuppression in mice. Present study, therefore, reveals that the drug holds promiseas immunomodulatory agent, which acts by stimulating both humoral as well as cellular immunity and phagocyticfunctionDownloads
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