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Abstract
The aminoglycoside antibiotics modifying enzymes and their genetic properties from 97 entero bacteria strains resistant to several aminoglycoside antibiotics isolated at the Universitary Hospital of Granada were studied. These enzymes were detected in 82 strains (84,5 %) and their genetics determinants were localized in 74 strains (90,2 %) on conjugative plasmids. 8 strains (9,8 %) had their genetics determinant on plasmid transferred only by transformation. Four types of enzymes were found, APH(3'), AAC(3), AAC(6') and ANT(2") in this strains. Our results show a situation of endemic resistance towards those antibiotics without control in this hospital.
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