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Abstract
A study on the relaxing effect'of sorne terpenic derivates, with oxygen (linalool) and without oxygen (alfa-pinene, sabinene and limonene), major components from essential oil of J. sabina L., over smooth muscle has been performed. Contraction rat isolated uterus was induced by increasing doses of oxytocin (10-10 - 10-9M). The results obtaines showed that ter penes (2,5 . 10-4M) have relaxing activity of uterus "in vitro" (non competitive antogonism with oxytocin dose depent). The use of emulsifier (sodium cholate) for help to solubility of terpenes in the water don't modifity the results obtaines when the ter penes have been homogeneity in the water for agitation.
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