Español

Authors

  • Español
  • Español
  • Español

Keywords:

Español

Abstract

Nitric oxide (NO) is a free gas enzymatically synthetized and with a short half lije. NO has important functions in the cardiovascular (vasodilator) and nervous (neurotransmitter) systems. However, NO is not a typical intercellular messenger since it is highly dijfusible and does not bind to cellular receptors. In this paper, we will review the actions of NO on the exocrine pancreas. The most classical studies demonstrated that NO stimulates pancreatic blood flow and thereby exocrine pancreatic secretion, but, additionally it might have some stimulatory effects on pancreatic acinar and ductal cells. It has been recently reported that acinar pancreatic cells can produce NO after secretagogue stimlllation. NO has a modulatory effect on secretagoglle stimulation of pancreatic enzyme secretion and it influences tyrosine phosphorylation of some acinar cytoskeletal proteins. Finally, NO seems to be in volved in tissue damage derived from pancreatitis.

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Published

1999-06-20

How to Cite

1.
Español, Español, Español. Español. Ars Pharm [Internet]. 1999 Jun. 20 [cited 2024 May 17];40(3):143-50. Available from: https://revistaseug.ugr.es/index.php/ars/article/view/24700

Issue

Vol. 40 No. 3 (1999)

Section

Original Articles

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