Toxic effects of antineoplastic therapy in patients breast cancer in Caruaru-PE oncology center
DOI:
https://doi.org/10.30827/ars.v59i4.8113Keywords:
Antineoplastic Agents, Breast Neoplasms, Drug-Related Side Effects and Adverse Reactions, Cancer, Medical oncologyAbstract
Objective: to evaluate the main clinical symptoms associated with the toxic effects of antineoplastic therapy in women with breast cancer at a cancer treatment center in the city of Caruaru/PE.
Methods: This is an analytical and transversal study with a quantitative approach, carried out between September and December 2017, whose data source was the medical records of the patients included in the study.
Results: the majority of the sample consisted of women aged between 41 and 50 years (28.6%). This study made it possible to identify the most frequent histological type of breast cancer, with invasive ductal carcinoma observed in 88.6% and the most used protocol was Doxorubicin, Cyclophosphamide and Paclitaxel. Alopecia (91.4%) was the main adverse event observed in patients.
Conclusion: it was possible to verify that the observation of these effects, allows a better control during the therapy, enabling improvement of the time and quality of life.
Downloads
References
Brazil. Ministry of Health. National Cancer Institute – INCA. Câncer de Mama. Available in: http://www2.inca.gov.br/wps/wcm/connect/tiposdecancer/site/home/mama. Access in: Feb 20, 2018.
Garcia SN, Jacowski M, Castro GC, Galdino C, Guimarães PRB, Kalinke LP . Quality of life domains aff ected in women with breast cancer. Rev Gaúcha Enferm. 2015;36:89-96. doi:10.1590/1983-1447.2015.02.45718.
Furlan VLA, Neto MS, Abla LEF, Oliveira CJR, Lima AC, Ruiz BFO et al. Quality of life and self-esteem after mastectomy in patients who did or did not undergo breast reconstruction. Rev Bras Cir Plást. 2013;28:264-269. doi:10.1590/S1983-51752013000200016.
Almeida VL, Leitão A, Reina LCB, Montanari CA, Donnici CL, Lopes MTP . Câncer e agentes antineoplásicos ciclo-celular específicos e ciclo-celular não específicos que interagem com o DNA: uma introdução. Quím Nova. 2005;28:118-129. doi:10.1590/S0100-40422005000100021.
Cavalcanti IDL, Volpini NA, Santos RJ, Coimbra CGO. Interações fármaco-nutriente na terapia antineoplásica: uma revisão integrativa da literatura. Rev Bras Farm. 2017;98(3):2256-2273.
Gozzo TO, Souza SG, Moysés AMB, Panobianco MS, Almeida AM. Incidence and management of chemotherapy-induced nausea and vomiting in women with breast cancer. Rev Gaúcha Enferm. 2014;35:117-123. doi:10.1590/1983-1447.2014.03.42068.
Silva WP, Silva JMFL, Santos FAV, Paiva SU, Ramalho GSA). Análise do perfil de diagnóstico de câncer de mama em um serviço de atenção secundária à saúde. Revista Eletrônica Acervo Saúde. 2018;10: 1459-1465. doi:10.25248/REAS136_2018.
Pinheiro AB, Lauter DS, Medeiros GC, Cardozo IR, Menezes LM, Souza RMB et al. Câncer de Mama em Mulheres Jovens: Análise de 12.689 Casos. Rev Bras Cancerol. 2013;59:351-359.
Coelho JMF, Santos BM, Miranda SS, Porto EC, Monção MM, Silva CS et al. Percepção da condição bucal de pacientes sob tratamento oncológico em uma unidade de alta complexidade em Feira de Santana – BA. Rev Saúde Col UEFS. 2016;6:51-58. doi:10.13102/rscdauefs.v6i2.1163.
Coelho RCFP. Qualidade de vida de mulheres com câncer de mama em tratamento quimioterápico adjuvante e neoadjuvante [mestrado]. Universidade Federal do Paraná; Curitiba, 2015.
Bushatsky M, Silva RA, Lima MTC, Barros MBSC, Neto JEVB, Ramos YTM. Quality of life in women with breast cancer in chemotherapeutic treatment. Cienc Cuid Saude . 2017;16:1-7. doi:10.1097/NCC.0000000000000370.
Reis APA, Gradim CVC. A alopecia no câncer de mama. Rev enferm UFPE. 2018;12:447-455. doi:10.5205/1981-8963-v12i2a25097p447-455-2018
Gozzo TO, Moyses AMB, Silva PR, Almeida AM. Nausea, vomiting and quality of life in women with breast cancer receiving chemotherapy. Rev Gaúcha Enferm. 2013;4:110-116. doi:10.1590/S1983-14472013000300014.
Tolentino GP. Avaliação da composição corporal, qualidade de vida e toxicidade do tratamento quimioterápico em mulheres com câncer de mama. [doutorado]. Universidade de Brasília; Brasília, 2016.
Sanches-Junior JA, Brandt HRC, Moure EMD, Pereira GLS, Criado PR. Adverse mucocutaneous reactions to chemotherapeutic agents - Part I. An Bras Dermatol. 2010;85:425-437. doi:10.1590/S0365-05962010000400003.
Published
How to Cite
Issue
Section
License
Copyright (c) 2018 Rayssa Almeida Carneiro, Ana Caroline de Brito França, Sabryna Aleadynah Barbosa da Silva, Iago Dillion Lima Cavalcanti, Analúcia Guedes Silveira Cabral, Adrya Lucia Peres

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The articles, which are published in this journal, are subject to the following terms in relation to the rights of patrimonial or exploitation:
- The authors will keep their copyright and guarantee to the journal the right of first publication of their work, which will be distributed with a Creative Commons BY-NC-SA 4.0 license that allows third parties to reuse the work whenever its author, quote the original source and do not make commercial use of it.
b. The authors may adopt other non-exclusive licensing agreements for the distribution of the published version of the work (e.g., deposit it in an institutional telematic file or publish it in a monographic volume) provided that the original source of its publication is indicated.
c. Authors are allowed and advised to disseminate their work through the Internet (e.g. in institutional repositories or on their website) before and during the submission process, which can produce interesting exchanges and increase citations of the published work. (See The effect of open access).