Medical treatment of benign prostatic hyperplasia
Abstract
Benign prostatic hyperplasia is a nonmalignant enlargement of the pros tate. This
condition is very common in men over sixty years of age and causes bladder outflow
osbstrucion. There are also irritative symptomes produced by urethral hypertonia of
neurologycal origin through alpha-l-adrenergic receptors. Androgenic suppressión is used
to treat the enlargement of the prostate whereas irritative symptomes are treated with
alpha-I-adrenoreceptor antagonists. Finasteride blocks the conversión of testosterone to
dihydrotestosterone, which is the active fonn of the honnone in the pros tate. Alfuzosin
is an alpha-l-adrenoreceptor antagonist in the genitourinary tract.
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