Alginate microspheres for dermatopharmaceutical use

Authors

  • AC RODRÍGUEZ-LLIMÓS Departamento de Tecnología Farmacéutica, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires Junín
  • C BREGNI Departamento de Tecnología Farmacéutica, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires Junín
  • C Y DE LOS SANTOS-CARVALLIDO Laboratorio Dérmico Farmacéutico, Montevideo, Uruguay

Keywords:

All-trans-retinoic acid, Tretinoin, Vitamin A acid, Dermatopharmacy, Microspheres, Salicylic acid, Sodium alginate

Abstract

Simple and reproducible methods were developed to microencapsulate all-trans-retinoic acid (RA) and salicylic acid (SA)in solution. The objectives of the present study were to improve their therapeutic applications and to establish comparativecriteria concerning the different methodologies that have been used. The objective of RA and SA microencapsulationon the one hand, is to modulate AR release in an attempt to protect skin from AR and AS irritation and, on the other,is to protect RA from environmental hazards such as air, light and moisture.

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Published

2003-06-16

How to Cite

1.
RODRÍGUEZ-LLIMÓS A, BREGNI C, Y DE LOS SANTOS-CARVALLIDO C. Alginate microspheres for dermatopharmaceutical use. Ars Pharm [Internet]. 2003 Jun. 16 [cited 2024 Aug. 24];44(3):215-24. Available from: https://revistaseug.ugr.es/index.php/ars/article/view/5151

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Original Articles