Antimicrobial activity of centaurea solstitialis and centaurea calcitrapa

Authors

  • MS TORIBIO Cátedra de Farmacología
  • DS ORIANI Cátedra de Microbiología, Facultad de Ciencias Veterinarias, Universidad Nacional de la Pampa, c/5 y 116, (6360) General Pico (La Pampa), Argentina
  • MI SKLIAR Cátedra de Farmacognosia, Departamento de Biología, Bioquímica y Farmacia, Universidad Nacional del Sur, San Juan 670, (8000) Bahía Blanca, Argentina.

Keywords:

Centaurea solstitialis, Centaurea calcitrapa, Antimicrobial activity, Methanolic extracts, MIC, MBC, Abrepuño

Abstract

Centaurea solstitialis and Centaurea calcitrapa (Asteraceae), commonly known as Abrepuño amarillo and Abrepuñocolorado respectively, are weeds that grow in the Province of Pampea Argentina, the former of which being the mostabundantly encountered species. Research carried out in other countries has demonstrated that the genus Centaureapossesses antimicrobial properties. The objective of this work was to ascertain the extent to which such a biological activitymay be present in these species, found growing in this particular Argentinian Province. Minimum Inhibitory Concentrationand Minimum Bactericide Concentration was evaluated by means of the dilution method, in broth of methanolic extractsof dry heads of both species. The results obtained, under the working conditions of this study, demonstrated thatCentaurea calcitrapa, presents antimicrobial activity against four of the ten assayed strains: Pseudomonas aeruginosa,Staphylococcus aureus, Streptococcus agalactiae and Salmonella typhimurium, while Centaurea solstitialis showsantibacterial activity to a lesser extent, with inhibitory activity only being found against two strains: Streptococcusagalactiae and Staphylococcus aureus.

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References

Font Quer P. Plantas Medicinales. El Dioscórides Renovado. Editorial Labor S.A., Barcelona, España; 1995: p. 850-852.

Yesilada E, Sezik E, Fujita T, Tanaka S, Tabata M. Screening of some Turkish medicinal plants for their antiulcerogenic activities. Phytotherapy Res 1993; 7: 263-265.

Kamanzi P, Voirin B, Raynaud ET. Methoxi flavonoids from the flowers of Centaurea solstitialis L. (Compositae). Plant Méd Phytothér 1983; 17: 52-56.

Masso JL, Bertran MN, Adzet T. Contribution to a chemical and pharmacological study of several species of Centaurea

(Compositae). Plant Méd Phytothér 1979; 13:41-45.

Ríos JL, Recio MC, Villar A. Antimicrobial activity of selected plants employed in the spanish mediterranean area. J Ethnopharmacol 1987; 21: 139-152.

Frontera MA, Tomas MA, Brunengo MC, Badajos MA, Tombesi OL, Ponce MA, et al. Estudio químico de la maleza Centaurea calcitrapa. Rev Latinoamer Quím 1991; 22: 29-31.

Hamburger M, Wolfender J, Hostettmann K. Search for chlorinated sesquiterpene lactones in the neurotoxic thistle Centaurea solstitialis by liquid chromatography mass spectrometry, and model studies on their possible artifactual formation. Natural Toxins 1993; 1: 315-327.

González A, Bermejo J, Massanet GM. Aportación al estudio quimiotaxonómico del género Centaurea: determinación estructural de las lactonas sesquiterpénicas presentes en centaureas de Canarias y de la península Ibérica. Rev Latinoamer Quim 1977; 8:176-180.

Jakupovic J, Jia Y, Pathak VP, Bohlmann F, King RM. Bisabolone derivatives and sesquiterpene lactones from Centaurea species. Planta Med 1986; 5: 399-401.

Karawya MS, Hilal SH, Hifnawy MS, El-Hawary SS. Isolation and preliminary pharmacological and microbiological screening of cnicin from Centaurea calcitrapa L. growing in Egypt. Egypt J Pharm Sci 1975; 4: 445-455.

Yesilada E, Gurbuz I, Shibata H. Screening of Turkish antiulcerogenic folk remedies for anti-Helicobacter pylori activity.

J Ethnopharmacol 1999; 3: 289-293.

Leiva J. Determinación de la concentración mínima inhibitoria y de la concentración mínima bactericida. En: Díaz R, Gamazo C, López Goñi I. Editor. Manual Práctico de Microbiología. Editorial Masson, España; 1995: p. 127.

Bauer AW, Kirby WMM, Sherris JC, Truck M. Antibiotic susceptibility testing by a standardized single disk method. Amer J Clin Pathol 1966; 45: 493-496.

Evans WC. Farmacognosia, Trease-Evans, 13ª Edición. Editorial Interamericana, Mc Graw-Hill, México D.F., México;

: p. 85-90. (Footnotes)

Published

2004-09-20

How to Cite

1.
TORIBIO M, ORIANI D, SKLIAR M. Antimicrobial activity of centaurea solstitialis and centaurea calcitrapa. Ars Pharm [Internet]. 2004 Sep. 20 [cited 2024 Jul. 22];45(4):281-9. Available from: https://revistaseug.ugr.es/index.php/ars/article/view/5117

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Original Articles