In vitro antioxidant activity of methanol extract of rhizomes of Curculigo orchioides Gaertn

Authors

  • AR BAFNA Departamento de Farmacia, Facultad de Tecnología e Ingeniería, The M.S.University of Baroda, Vadodara-390002, Gujarat, India
  • SH MISHRA Departamento de Farmacia, Facultad de Tecnología e Ingeniería, The M.S.University of Baroda, Vadodara-390002, Gujarat, India

Keywords:

Antioxidant activity, DPPH, Superoxide, Reducing power

Abstract

Methanol extract of Curculigo orchioides was screened for in- vitro antioxidant activity using DPPHassay, superoxide scavenging, nitric oxide scavenging, determination of reducing power and in-vitrolipid peroxidation.Methanol extract was found to be extremely effective in scavenging superoxide radical (IC50 29.28 μg/ml) whereas activity was moderate in scavenging DPPH radical (IC50 105.94 μg/ml), nitric oxide radical(IC50 90.96 μg/ml) and in inhibition of lipid peroxidation (IC50 94.78 ìg/ml). Methanol extract showeddifferent levels of antioxidant activities in tested models. It also supported anti oxidant activity byshowing significant reducing power. Further HPTLC finger print profile of the methanol extract wasestablished to facilitate its identification and characterization.Present study demonstrated antioxidant activity of methanol extract of Curculigo orchioides in-vitro.

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Published

2005-03-20

How to Cite

1.
BAFNA A, MISHRA S. In vitro antioxidant activity of methanol extract of rhizomes of Curculigo orchioides Gaertn. Ars Pharm [Internet]. 2005 Mar. 20 [cited 2024 Jul. 22];46(2):125-38. Available from: https://revistaseug.ugr.es/index.php/ars/article/view/5067

Issue

Vol. 46 No. 2 (2005)

Section

Original Articles

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