Stabilized liquid-crystalline emulsions with triethanolamine stearate and stearic acid: preparation method infl uence in the properties and formation of secondary droplets

Authors

  • RC PASQUALI Departamento de Tecnología Farmacéutica, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires
  • C BREGNI Departamento de Tecnología Farmacéutica, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires

Keywords:

Emulsions, Lyotropic liquid crystals, Secondary droplets, Triethanolamine stearate

Abstract

It has been developed a methodology which allows obtaining mineral oil emulsions stabilized with triethanolamine stearateand stearic acid with liquid-crystalline characteristics where droplets cluster themselves forming secondary dropletsof 15 μm diameter. The formation of the mentioned secondary droplets, which are a consequence of the presence oflyotropic liquid crystals in the emulsions, produces a diminution of the viscosity. The replacement of part of the mineraloil of these emulsions for others emollients with greater dermal penetration capacity, such as isopropyl myristate and2-octyl-1-dodecanol, does not diminish the liquid-crystalline characteristics, granting the obtainment of more adequateemulsions for pharmaceutical and cosmetic usage.

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Published

2006-06-20

How to Cite

1.
PASQUALI R, BREGNI C. Stabilized liquid-crystalline emulsions with triethanolamine stearate and stearic acid: preparation method infl uence in the properties and formation of secondary droplets. Ars Pharm [Internet]. 2006 Jun. 20 [cited 2024 May 18];47(2):219-37. Available from: https://revistaseug.ugr.es/index.php/ars/article/view/5028

Issue

Vol. 47 No. 2 (2006)

Section

Original Articles

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