An evaluation of polyphenol release from cosmetic formulations
Keywords:
Release, Polyphenols, Grape therapyAbstract
One of the proposed treatments for extrinsic skin aging processes is Grape therapy, whose active ingredients, knownto possess antioxidant properties, are the vegetable and seed oil extracts from the Vitis Vinífera L. grape species. Theobjective of the present work was to evaluate the release of polyphenol compounds from these extracts, retained ingel and emulsion based cosmetic formulations, using Franz diffusion cells. A quantifi cation of total active ingredientrelease was also carried out using the Folin Denis visible spectrophotometry method. Polyphenol release from bothtypes of formulation was found to follow a square root of time kinetic model, but a higher rate of release was obtainedfrom the gel formulation.Downloads
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