Effect of surfactant on the release of ciprofloxacin from gelatin microspheres

Authors

  • S Kesavan Department of Biochemistry
  • Swarnambal Alamelu Bai Department of Biochemistry

Keywords:

Microspheres, Surfactants, Ciprofloxacin, Glutaraldehyde

Abstract

Gelatin microspheres with high entrapment efficiency were prepared by emulsification (using differentsurfactants) and crosslinking by glutaraldehyde with a view to improve stability of the microspheres.The microspheres were characterized for entrapment efficiency of ciprofloxacin, swelling, FT-IR,scanning electron microscopy (SEM) and leakage properties.From the results obtained we inferred thatthe gelatin microspheres entrapped with ciprofloxacin prepared by using three different surfactantsincreased the shelf life of gelatin microspheres.

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Published

2010-03-20

How to Cite

1.
Kesavan S, Alamelu Bai S. Effect of surfactant on the release of ciprofloxacin from gelatin microspheres. Ars Pharm [Internet]. 2010 Mar. 20 [cited 2025 Jan. 15];51(1):1-16. Available from: https://revistaseug.ugr.es/index.php/ars/article/view/4841

Issue

Vol. 51 No. 1 (2010)

Section

Original Articles

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