Formulation, Development and Evaluation of Herbal Pediatric Edible Jelly for Cough

Authors

  • Khemchand Surana Department of Pharmaceutical Chemistry, SSS’s Divine College of Pharmacy, Nampur Road, Satana, Nashik, Maharashtra https://orcid.org/0000-0001-8918-1159
  • Vaishali Sonawane Department of Pharmaceutical Chemistry, SSS’s Divine College of Pharmacy, Nampur Road, Satana, Nashik, Maharashtra
  • Chaitali Yeola Department of Pharmaceutical Chemistry, SSS’s Divine College of Pharmacy, Nampur Road, Satana, Nashik, Maharashtra
  • Jayesh Musale Department of Pharmaceutics, Mahatma Gandhi Vidyamandir’s SPH College of Pharmacy, Malegaon, Nashik, Maharashtra
  • Sunil Mahajan Department of Pharmaceutical Chemistry, SSS’s Divine College of Pharmacy, Nampur Road, Satana, Nashik, Maharashtra
  • Deepak Sonawane Department of Pharmaceutics, SSS’s Divine College of Pharmacy, Nampur Road, Satana, Nashik, Maharashtra
  • Vijayraj Sonawane Department of Pharmaceutical Chemistry, SSS’s Divine College of Pharmacy, Nampur Road, Satana, Nashik, Maharashtra
  • Raj Keservani Faculty of B. Pharmacy, CSM Group of Institutions, Prayagraj, Uttar Pradesh

DOI:

https://doi.org/10.30827/ars.v66i1.31428

Keywords:

Pediatrics, Edible jellies, Ocimum sanctum, Glycyrrhiza glabra, Adhatoda vasika, Elettaria cardamomum, Zingiber officinale, Mentha piperita, Eugenia caryophyllus, Cinnamomum zeylanicum, Honey

Abstract

Introduction: The children’s resistance to dosage regimens is one of the challenging issues in pediatric therapy. There are two significant issues with pediatric patients: a lack of self-drug administration skills and patient compliance. The medical characteristics of herbs have become increasingly important due to their lack of side effects, low cost, and biocompatibility. 

Method: The herbs that will be used are Ocimum sanctum (Tulsi), Adhatoda vasika (Adulsa), Elettariacardamomum (Cardamom), Zingiberofficinale (Ginger), Mentha piperita (Peppermint), Glycyrrhiza glabra (Liquorice), Eugenia caryophyllus (Clove), Cinnamomum zeylanicum (Cinnamon), and Honey. The formulation were prepared by decoction method and evaluated.

Results: These herbs’ extracts show good antimicrobial activity against E. coli. The formulated jelly shows good appearance, pH, disintegration, and spreadability. We conduct a 6-month stability study on the formulated jelly. It has a good appearance and does not change pH. So, the formulated jelly can be stable for up to 6 months.

Conclusions: The data revealed that the optimized formulation had not shown any change in their appearance or pH. So, the formulated jelly can be stable for up to 6 months. The formulations exhibited excellent antimicrobial activity, which is suitable to administer to children as an alternative oral solid dosage form.

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Published

2024-12-20

How to Cite

1.
Surana K, Sonawane V, Yeola C, Musale J, Mahajan S, Sonawane D, Sonawane V, Keservani R. Formulation, Development and Evaluation of Herbal Pediatric Edible Jelly for Cough. Ars Pharm [Internet]. 2024 Dec. 20 [cited 2025 Jul. 8];66(1):89-100. Available from: https://revistaseug.ugr.es/index.php/ars/article/view/31428

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