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Abstract
Gluconeogenic and glycolytic capacities as well as the most important enzymes of these processes have been studied in isolated renal tubules under different nutritional conditions. During a high-carbohydrate diet there is a parallelism between the changes in gluconeogenic and glycolytic processes and the enzymes involved in these processes. Whereas with a high-protein diet the glycolytic behaviour clearly indicate a high flux of the mitochondrial metabolism. Finally, during starvation, besides the activity of the enzyme assayed, the opposite effect in renal glucose synthesis and oxidation appears to be related to other molecular aspects involve in these processes.
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