Post-transcriptional mechanisms regulating hsp70 gene expression in Leishmania

Authors

  • L. QUIJADA
  • J.M. REQUENA
  • M. SOTO
  • C. ALONSO

Keywords:

Trypanosomatids, Gene expression, Regulation, Post-transcriptional mechanisms.

Abstract

Trypanosomatids represent one of the earlier groups of eukaryotic organisms in evolution. During their long evolutionary history, the trypanosomatids have developed an impressive variety of life styles and adaptations to parasitism. The parasitic cycle of these organisms is characterized by a succesion of different forms adapted to the different environments they encounter in their mammalian hosts and insect vectors. Perhaps as a reflection of their ancient origin, these organisms posses a variety of unusual molecular mechanisms that result in regulated gene expression. In this context, a general feature of gene expression in these protozoan parasites is its high regulation at post-transcriptional level. In this work, some recent advances in understanding the mechanisms of gene express ion in trypanosomatids and its regulation are discussed.

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References

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Published

1997-03-20

How to Cite

1.
QUIJADA L, REQUENA J, SOTO M, ALONSO C. Post-transcriptional mechanisms regulating hsp70 gene expression in Leishmania . Ars Pharm [Internet]. 1997 Mar. 20 [cited 2024 Jul. 22];38(2-3):305-17. Available from: https://revistaseug.ugr.es/index.php/ars/article/view/21218

Issue

Vol. 38 No. 2-3 (1997)

Section

Original Articles

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