Flavonoides y enfermedad inflamatoria intestinal

Autores/as

  • I BALLESTER Departamento de Farmacología, Facultad de Farmacia, Universidad de Granada, Campus Universitario ‘La Cartuja’ s/n, 18071 Granada (España)
  • D CAMUESCO Departamento de Farmacología, Facultad de Farmacia, Universidad de Granada, Campus Universitario ‘La Cartuja’ s/n, 18071 Granada (España)
  • J GÁLVEZ Departamento de Farmacología, Facultad de Farmacia, Universidad de Granada, Campus Universitario ‘La Cartuja’ s/n, 18071 Granada (España)
  • F SÁNCHEZ DE MEDINA Departamento de Farmacología, Facultad de Farmacia, Universidad de Granada, Campus Universitario ‘La Cartuja’ s/n, 18071 Granada (España)
  • A ZARZUELO Departamento de Farmacología, Facultad de Farmacia, Universidad de Granada, Campus Universitario ‘La Cartuja’ s/n, 18071 Granada (España)

Palabras clave:

Antioxidante, Citocina, Enfermedad Inflamatoria Intestinal, Flavonoide, Leucotrieno B4, NFκB, Łxido nítrico

Resumen

Estudios epidemiológicos han puesto en evidencia el papel que tienen los alimentos de origen vegetal en la prevenciónde numerosas enfermedades. Los antioxidantes naturales presentes en estos alimentos, entre los que destacanlos fl avonoides, pueden ser responsables de esta actividad. Los fl avonoides son compuestos de bajo peso molecularque se encuentran ampliamente distribuidos en el reino vegetal. Pueden mejorar los estados de diarrea aguda ycrónica a través de la inhibición de la secreción y motilidad intestinal y también ser muy útiles en la reducción deldaño infl amatorio crónico en el intestino, protegiéndolo del estrés oxidativo y preservando la función de la mucosa.Por ello, se proponen como agentes terapéuticos en el tratamiento de la Enfermedad Infl amatoria Intestinal, en laque factores diversos promueven una reacción inmunológica exacerbada que conduce a una infl amación crónicadel intestino.

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2006-03-20

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1.
BALLESTER I, CAMUESCO D, GÁLVEZ J, SÁNCHEZ DE MEDINA F, ZARZUELO A. Flavonoides y enfermedad inflamatoria intestinal. Ars Pharm [Internet]. 20 de marzo de 2006 [citado 28 de abril de 2024];47(1):5-21. Disponible en: https://revistaseug.ugr.es/index.php/ars/article/view/5021

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