Development and Evaluation of Moisturizing Cream containing Salvia hispanica and Aloe vera and its Antioxidant Potential

Rutuja K. Deore; Khemchand Surana; Sunil K. Mahajan; Rushikesh L. Bachhav; Deepak D. Sonawane

doi:10.30827/ars.v66i3.32785

Autores/as

Rutuja K. Deore Department of Pharmaceutical Quality Assurance, SSS’s Divine College of Pharmacy Satana, Nashik, Maharashtra
Khemchand Surana Department of Pharmaceutical Chemistry, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, Affiliated to SavitribaiPhule Pune University, Pune, Maharashtra 423301, India
Sunil K. Mahajan Department of Pharmaceutical Chemistry, SSS’s Divine College of Pharmacy, Satana, Nashik, Maharashtra
Rushikesh L. Bachhav Department of Pharmaceutical Quality Assurance, SSS’s Divine College of Pharmacy Satana, Nashik, Maharashtra
Deepak D. Sonawane Department of Pharmaceutics, SSS’s Divine College of Pharmacy, Nashik, Maharashtra

DOI:

https://doi.org/10.30827/ars.v66i3.32785

Palabras clave:

Aloe vera, Salvia hispanica, Chia, Moisturizing cream, antioxidant

Resumen

Introducción: Los bioactivos presentes en las semillas de Salvia hispánica (chía) y el aloe vera hidratan, protegen y restauran la piel. El objetivo de este trabajo es formular y evaluar una crema herbal multifuncional con mucílago de semilla de Salvia hispánica, gel de aloe vera, manteca de karité y aceite de coco para hidratar y restaurar la piel.

Métodos: El extracto de semilla de Salvia hispánica se obtuvo mediante la extracción del mucílago. Se preparó gel de aloe vera y se incorporó a la fórmula junto con manteca de karité y aceite de coco. La fórmula final de la crema se evaluó en cuanto a parámetros fisicoquímicos como pH (6), extensibilidad (7,5 g/s), consistencia, lavabilidad y ausencia de irritación. Se realizó un ensayo de depuración de peróxido de hidrógeno para determinar la actividad antioxidante.

Resultados: La crema formulada demostró actividad antioxidante y reveló una significativa capacidad de eliminación de peróxido de hidrógeno del 95,16 %, lo que indica un alto potencial de eliminación de radicales. La formulación presentó características fisicoquímicas deseables.

Conclusión: Este estudio descubrió que la crema tiene actividad antioxidante con su composición natural y componentes vegetales beneficiosos, podría ser una solución eficaz y sostenible para el cuidado de la piel.

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