Metabolic alterations induced by tumour growth during the perinatal phase

Autores/as

  • J. M. Argilés
  • N. Carbó
  • F. J. López-Soriano

Resumen

The implantation of a fast-growing tumour is associated with severe metabolic

complications in the host, leading to cachexia and finally death. In contrast, the

implantation of the fast-growing Yoshida AH-l30 ascites hepatoma to pregnant rats at

term did not result in any changes in fetal growth, the availability of amino acids for

the fetus being unchanged by tumour burden. Similarly, the implantation of the fastgrowing

rat Walker 256 carcinosarcoma resulted in very little changes in lipid metabolism

during lactation, the metabolism of the mammary gland being basically unaffected by

the presence of the tumour. It may be suggested that during the perinatal phase the

mother can cope with sorne of the metabolic disturbances induced by tumours this

being able to protect either the fetus or the newbom.

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Citas

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Publicado

1996-12-20

Cómo citar

1.
Argilés JM, Carbó N, López-Soriano FJ. Metabolic alterations induced by tumour growth during the perinatal phase. Ars Pharm [Internet]. 20 de diciembre de 1996 [citado 7 de mayo de 2024];37(4):907-20. Disponible en: https://revistaseug.ugr.es/index.php/ars/article/view/21754

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