EfIect of physical training on insulin response in late pregnancy rats

Autores/as

  • C. Muñoz
  • P. LÓPEZ-LUNA
  • E. Herrera

Palabras clave:

Pregnancy, Rat, glucose and insuline, tolerance, excersise, endocrine pancreas

Resumen

Oral glucose tolerance test (2 glKg body weigth) produced parallel changes in

blood glucose in both 20 day pregnant and virgin rats whereas plasma RIA -insulin

increased more in the pregnant animals indicating insulin resistance. This study was

addressed to determine whether a moderate maternal aerobic exercise throughout gestation

modifies insulin responsiveness in the mother. Virgin and pregnant rats subjected or not

to a treadmill running 10° grade for 5 days per week at 20 mlmin until 75 min on 20

day of protocol andJor gestation were subjected to an intravenous tolerance test with 10

IV of porcine insulinIKg body weight. The integrated hypoglycemic effect of intravenous

insulin adrninistration showed an enhanced insulin responsiveness in the exercised

pregnant rats as compared to non-exercised animals, with no effect in virgin rats

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Citas

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LETURQUE, A., FERRE, P., BURNOL, A. F., KANDE, J., MAULARD, P., GIRARD,
J.: Diabetes (1986), 35: 172-177.

SILVERSTONE, F. A. , SOLOMON, E., RUBRICIUS, J. : J Clin Invest (1961), 40:
2180-2189.

EDSTROM, K., CERASI, E., LUFT, R.: Acta Endocrinol (1968), 75: 87-104.

PICARD, c., OOMS, H. A., BALAS SE, E.: Diabetologia (1968), 4: 16-19.

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Publicado

1996-12-20

Cómo citar

1.
Muñoz C, LÓPEZ-LUNA P, Herrera E. EfIect of physical training on insulin response in late pregnancy rats. Ars Pharm [Internet]. 20 de diciembre de 1996 [citado 13 de noviembre de 2024];37(4):897-906. Disponible en: https://revistaseug.ugr.es/index.php/ars/article/view/21753

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