Alginate microspheres for dermatopharmaceutical use
Keywords:
All-trans-retinoic acid, Tretinoin, Vitamin A acid, Dermatopharmacy, Microspheres, Salicylic acid, Sodium alginateAbstract
Simple and reproducible methods were developed to microencapsulate all-trans-retinoic acid (RA) and salicylic acid (SA)in solution. The objectives of the present study were to improve their therapeutic applications and to establish comparativecriteria concerning the different methodologies that have been used. The objective of RA and SA microencapsulationon the one hand, is to modulate AR release in an attempt to protect skin from AR and AS irritation and, on the other,is to protect RA from environmental hazards such as air, light and moisture.Downloads
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