Efecto de compuestos fitoquímicos del género Allium sobre el sistema inmune y la respuesta inflamatoria

Enrique Guillamon

Resumen


Objetivos: Revisión y discusión de las evidencias científicas sobre los efectos de los compuestos organosulfurados de vegetales del género Allium como inmunomoduladores y potenciadores de la respuesta inmune.

Métodos: Se realizó una revisión de estudios científicos originales y documentos de revisión.

Resultados: Son numerosos los estudios científicos que evidencian la estrecha relación existente entre alimentación y salud, demostrando los beneficios que vitaminas, minerales, ácidos grasos poliinsaturados, probióticos, prebióticos o fitoquímicos ejercen sobre diversas patologías. Entre ellos, se destaca el papel de las sustancias de origen vegetal, como carotenoides, compuestos fenólicos, alcaloides, compuestos nitrogenados y organosulfurados, por su influencia positiva sobre la microbiota, salud intestinal y sistema inmune. En este trabajo se revisan y discuten las evidencias científicas sobre los beneficios de algunos compuestos organosulfurados de vegetales del género Allium, como alicina o propil propano tiosulfonato, por sus propiedades inmunomoduladoras y potenciadoras de la respuesta inmune.

Conclusiones: Numerosos trabajos científicos ponen de manifiesto el efecto positivo de los compuestos organosulfurados de vegetales del género Allium sobre el sistema inmune y los procesos inflamatorios. En particular de compuestos como la alicina, aunque su inestabilidad dificulta su aplicación real en suplementos nutracéuticos y otros compuestos, como los derivados de la propiína, resultan más prometedoras como ingredientes funcionales inmunopotenciadores.


Palabras clave


género Allium; compuestos organosulfurados; inmunidad; inflamación

Citas


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Fecha de actualización: 11- 03-2018

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