Isoflavonoids from the rhizomes of Iris hungarica and antibacterial activity of the dry rhizomes extract

Autores/as

  • Olga Mykhailenko Department of Botany, National University of Pharmacy, Kharkiv, Ukraine.
  • Volodumur Kovalyov Department of Pharmacognosy, National University of Pharmacy, Kharkiv, Ukraine
  • Sergiy Kovalyov Department of nutritiology and pharmaceutical bromatology, National University of Pharmacy, Kharkiv, Ukraine
  • Anastasiia Krechun Department of Pharmacognosy, National University of Pharmacy, Kharkiv, Ukraine

DOI:

https://doi.org/10.30827/ars.v58i1.5919

Palabras clave:

isoflavonoides, teсtorigenina, tectoridina, mangiferina, Iris hungarica, actividad antibacteriana

Resumen

Objetivo: El objetivo del trabajo es el aislamiento y la identificación de los compuestos fenólicos de losrizomas de Iris hungarica.

Materiales y métodos: Se utilizaron métodos químicos y espectrales para conocer las estructuras de compuestosfenólicos que se aislaron de los rizomas de Iris hungarica Waldst. et Kit. (Familia de Iridaceae).Los compuestos se obtuvieron mediante cromatografía en columna sobre gel de sílice y se determinaronsus estructuras mediante análisis de sus espectros por UV, IR, MS, 1H-RMN. Se determinó el cribadopreliminar de la actividad antibacteriana.

Resultados: Se aislaron por primera vez de los rizomas de Iris hungarica (común en Ucrania)dos isoflavonas, teсtorigenina y tectoridina (nuevas para esta especie), el xantonoidemangiferina y los isoflavonoides daidzeina, genisteina y formononetina.El extracto seco de los rizomas de I. hungarica a una concentración de 1% ha mostrado la actividad inhibitoriamás alta para bacterias y hongos Gram-positivos.

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Publicado

2017-03-20

Cómo citar

1.
Mykhailenko O, Kovalyov V, Kovalyov S, Krechun A. Isoflavonoids from the rhizomes of Iris hungarica and antibacterial activity of the dry rhizomes extract. Ars Pharm [Internet]. 20 de marzo de 2017 [citado 19 de marzo de 2024];58(1):39-45. Disponible en: https://revistaseug.ugr.es/index.php/ars/article/view/5919

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